Cofactor transport and salvage

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  • nadD nadD, from JCVI-Syn3.0, regulates the enzymes and coenzymes present in Probable nicotinate-nucleotide adenylyltransferase
  • nadD nadD, from E. coli, encodes a protein from ATP + beta-nicotinate-D-ribonucleotide which is involved in both de novo biosynthesis and salvage of NAD+ and NADPH
  • MSC_0503 MSC_0503,from JCVI-Syn3.0, encodes for a protein which is involved with the storage of folate (a type of vitamin)
  • ygfA ygfA, from E. Coli, encodes for a protein which is involved with the storage of folate (a type of vitamin).
  • nadD nadD, from JCVI-Syn3.0, encodes a protein that utilizes ATP and β-nicotinate D-ribonucleotide to produce diphosphate and deamido-NAD+
  • nadD nadD from E. coli encodes a protein that utilizes ATP and β-nicotinate D-ribonucleotide to produce diphosphate and deamido-NAD+
  • nadE nadE, from E. coli, encodes for NH(3)-dependent NAD(+) synthetase, which catalyzes ATP-dependent amidation of deamido-NAD to form NAD+.
  • nadE nadE, from JCVI-Syn3.0, encodes for NH(3)-dependent NAD(+) synthetase, which catalyzes ATP-dependent amidation of deamido-NAD to form NAD+.
  • ecfA ecfA, from JCVI-Syn3.0, encodes for Energy-coupling factor transporter ATP-binding protein subunit A
  • EcfA1_1 EcfA1_1, from E. coli, encodes for Energy-coupling factor transporter ATP-binding protein subunit A
  • tauB tauB, from E. coli, encodes for taurine import ATP-binding protein, which is involved in taurine import
  • glyA glyA is necessary for catalyzing the conversion of serine to glycine and tetrahydrofolate
  • glyA glyA, from "E.coli" is necessary for catalyzing the conversion of serine to glycine and tetrahydrofolate
  • folC folC, from JCVI: catalyzes the addition of the glutamyl residue to dihydropteroate, forming dihydrofolate
  • folC folC, from E.coli: catalyzes the addition of the glutamyl residue to dihydropteroate, forming dihydrofolate
  • folE from JCVI: no information available.
  • nadD nadD from E.coli is involved in step 1 of the subpathway that synthesizes deamido-NAD(+) from nicotinate D-ribonucleotide
  • ribF (JCVI), ribF (E. Coli) ribF encodes the enzyme bifunctional riboflavin kinase/FMN adenylyltransferase. This is a bifunctional protein that aid in the chemical transformation of riboflavin into FMN and FAD (coenzymes).
  • nadK (JCVI), nadK (E. Coli) nadK encodes the protein NAD kinase, an allosteric enzyme that controls the concentrations of NADPH vs NADP+, and NADH vs NAD+. It is likely that this protein is essential for growth.
  • glyA encodes the protein Serine hydroxymethyltransferase, which catalyzes a reaction that forms a one-carbon carrier.
  • glyA encodes the protein Serine hydroxymethyltransferase, which catalyzes a reaction that forms a one-carbon carrier.
  • folC contributes to two reactions in the de novo folate biosynthetic pathway. It catalyzes a reaction resulting in dihydrofolate, as well as a reaction resulting in folylpolyglutamate derivatives.
  • folC contributes to two reactions in the de novo folate biosynthetic pathway. It catalyzes a reaction resulting in dihydrofolate, as well as a reaction resulting in folylpolyglutamate derivatives.
  • nadK From JCVI NAD kinase appears to be an allosteric enzyme, with activity tightly coupled to the NADPH/NADP+ and NADH/NAD+ ratios present in the cell.
  • nadK From E.Coli NAD kinase appears to be an allosteric enzyme, with activity tightly coupled to the NADPH/NADP+ and NADH/NAD+ ratios present in the cell.
  • rBif ribF encodes a bifunctional protein with riboflavin kinase and FMN adenylyltransferase activities. These enzymes transform riboflavin into the coenzyme forms of FMN and FAD, respectively.
  • rBif ribF encodes a bifunctional protein with riboflavin kinase and FMN adenylyltransferase activities. These enzymes transform riboflavin into the coenzyme forms of FMN and FAD, respectively.
  • ecfA ecfA encodes from JCVI-Syn3.0, encodes for Energy-coupling factor transporter ATP-binding protein subunit A.
  • nadE nadE encodes from JCVI-Syn3.0, encodes for NH(3)-dependent NAD(+) synthetase, which catalyzes ATP-dependent amidation of deamido-NAD to form NAD+.
  • MMSYN1_0381 mtnN Catalyzes the cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose.
  • EG11090 The mtn gene encodes 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase by catalyzing glycosidic bond cleavage in S-adenosylhomocysteine and 5'-methylthioadenosine.
  • MMSYN1_0432 metK catalyzes the formation of the sulfonium compound S-adenosylmethionine by cleaving it from ATP, and through the process releasing energy to the cell.
  • EG10589 metK catalyzes the formation of the sulfonium compound S-adenosylmethionine by cleaving it from ATP, and through the process releasing energy to the cell.