DNA repair

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  • apn1 apn1 for JCVI-Syn3.0, cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues
  • nfo nfo for E. Coli cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues
  • MMSYN1 0404 msnelson DNA repair protein RecO that aids in repairing damaged DNA using the RECFOR complex which functions in RecA-mediated replication recovery.
  • EG10831 msnelson E. Coli homolog for the DNA repair protein RecO that aids in repairing damaged DNA using the RECFOR complex which functions in RecA-mediated replication recovery.
  • MMSYN1_0046 msnelson Recombination protein RecR that aids in recombining DNA using the RECFOR complex which functions in RecA-mediated replication recovery.
  • EG10834 msnelson E. Coli homolog for the recombination protein RecR that aids in recombining DNA using the RECFOR complex which functions in RecA-mediated replication recovery.
  • MMSYN1 0611 - yuchenj Strips RNA primers from newly-synthesized DNA and replacing them with DNA. Duplicates existing DNA by using the parental DNA as a template to synthesize new strands.
  • EG10746 - yuchenj Strips RNA primers from newly-synthesized DNA and replacing them with DNA. Duplicates existing DNA by using the parental DNA as a template to synthesize new strands.
  • TDT_BOVIN This gene codes for terminal deoxynucleotidyl transferase (TdT), a template-independent DNA polymerase that is used in non-homologous end joining for DNA repair, as well as to generate random antibody sequences in the bovine immune system.
  • MMSYN1_0109_andreavz : AP endonuclease proteins in Mycoplasma Mycoides start the repair of AP sites in DNA by cleavage of the DNA backbone immediately 5′ of an AP residue, creating a single-nucleotide gap.
  • EG10651_andreavz : AP endonuclease proteins in E. Coli start the repair of AP sites in DNA by cleavage of the DNA backbone immediately 5′ of an AP residue, creating a single-nucleotide gap.
  • MMSYN1_0825_veeral The UvrABC repair system in Mycoplasma mycoides catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.
  • MMSYN1_0824_rperez4 The UvrABC repair system uvrA protein. The uvrA protein recognizes DNA lesions and recruits uvrB and uvrC proteins to start repairing DNA.
  • MMSYN1_0254_rperez4 The UvrABC repair system uvrC protein. The uvrC protein excises the DNA around the damaged region.
  • EG11062 The UvrABC repair system in E. coli catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.
  • MMSYN1_0611_dpantuso DNA polymerase 1 (Pol 1) is a key enzyme involved in the maintenance and replication of DNA, responsible for both a 5’ to 3’ exonuclease activity and a 3’ to 5’ proofreading exonuclease activity.
  • EG10746 DNA polymerase 1 (Pol 1) is a key enzyme involved in the maintenance and replication of DNA, responsible for both a 5’ to 3’ exonuclease activity and a 3’ to 5’ proofreading exonuclease activity.
  • MMSYN1_0097 This (unknown) gene seems to be part of DNA polymerase 1, which is important to DNA replication and repair. This gene specifically deals with the 5' to 3' exonuclease activity.
  • DSUP is a unique DNA-associating protein that contributes to tardigrades' exceptional tolerance to harsh environmental stresses.