DNA replication

From BioE80 Boot
Jump to: navigation, search

MMSYN1 0611 - yuchenj Strips RNA primers from newly-synthesized DNA and replacing them with DNA. Duplicates existing DNA by using the parental DNA as a template to synthesize new strands.

MMSYN1 0420 - yuchenj This gene codes for the alpha subunit of DNA polymerase III, an enzyme that catalyzes the polymerase activity of the holoenzyme complex.

EG10746 - yuchenj Strips RNA primers from newly-synthesized DNA and replacing them with DNA. Duplicates existing DNA by using the parental DNA as a template to synthesize new strands.

EG10238 - yuchenj This gene codes for the alpha subunit of DNA polymerase III, an enzyme that catalyzes the polymerase activity of the holoenzyme complex.

MMSYN1_0026_chao16 This gene codes for a protein similar to primosomal protein N (PriB) in E. coli. PriB is a single-stranded nucleotide binding protein that holds open the replication fork as part of the pre-primosomal complex.

MMSYN1_0303_chao16 polC/dnaE encodes the alpha subunit of DNA polymerase III, which adds nucleotides to an existing DNA strand based on a complementary template strand. The alpha subunit is part of the DNA polymerase core.

EG10764_chao16 priB codes for primosomal protein N (PriB) in E. coli. PriB is a single-stranded nucleotide binding protein that holds open the replication fork as part of the pre-primosomal complex.

EG10238_chao16 polC/dnaE encodes the alpha subunit of DNA polymerase III, which adds nucleotides to an existing DNA strand based on a complementary template strand. The alpha subunit is part of the DNA polymerase core.

MMSYN1_0690_veeral DNA ligase in Mycoplasma mycoides that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA.

EG10534 DNA ligase in E. coli that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA.

MMSYN1_0612 DnaE is the alpha subunit of DNA Polymerase III, a polymerase which is responsible for most of the replicative synthesis through activation of the holoenzyme complex.

EG10238 DnaE is the alpha subunit of DNA Polymerase III, a polymerase which is responsible for most of the replicative synthesis through activation of the holoenzyme complex.

MMSYN1_0002_kblevins DnaN is the beta subunit of DNA Polymerase III, which is responsible for the replicative synthesis in the holoenzyme complex in prokaryotes.

MMSYN1_0826_kblevins YqeN is the delta subunit of DNA Polymerase III, which is responsible for the replicative synthesis in the holoenzyme complex in prokaryotes.

EG11412 holA is the the delta subunit of DNA Polymerase III, which is responsible for the replicative synthesis in the holoenzyme complex in prokaryotes, specifically E. Coli.

EG10242 is the beta subunit of DNA Polymerase III, which is responsible for the replicative synthesis in the holoenzyme complex in prokaryotes, specifically E. Coli.

MMSYN1 0002 aaarif encodes for the beta subunit of DNA Polymerase III, which is needed to clamp DNA Polymerase III onto a DNA strand to initiate replicative synthesis.

EG10242 aaarif encodes for the beta subunit of DNA Polymerase III in E.Coli, which is the clamping subunit of the major replicative synthesis complex in prokaryotes.

MMSYN1 0826 aaarif encodes for the delta subunit of DNA Polymerase III, which is the major replicative complex in bacteria.

EG11412 aaarif encodes for the delta subunit of DNA Polymerase III, which interacts with other subunits in the complex to allow proper replicative synthesis.

MMSYN1 0608 swmorris dnaB is a vital component in the chromosome replication process by elongating the chromosomes and initiating the replication process.

EG10236 swmorris dnaB is a vital component in the chromosome replication process by elongating the chromosomes and initiating the replication process.

MMSYN1 0609 swmorris dnaI creates a primosomal protein, dnaI, which is involved in prokaryotic DNA replication.

MMSYN1 0834 is dnaC which is a loading factor for dnaB helicase. It participates in initiation and elongation of DNA replication.

EG10236 is dnaB, replicative DNA helicase, which progressively unwinds DNA at replication forks.

MMSYN1 0001 is dnaA which initiates the process of replication by binding the the origin of replication.

EG10235 is dnaA in E.Coli which initiates the process of replication by binding the the origin of replication.

MMSYN1 0609 [1] is a gene the expresses the protein dnaB which initiates chromosomal replication.

holB (MMSYN1 0044) encodes the DNA Polymerase III Delta Prime Subunit, which is a component of the gamma complex subassembly that assembles the ring-shaped beta subunit onto ssDNA to form the beta sliding clamps.

holB (EG11500) encodes the DNA Polymerase III Delta Prime Subunit, which is a component of the gamma complex subassembly that assembles the ring-shaped beta subunit onto ssDNA to form the beta sliding clamps.

dnaX (MMSYN1 0047) encodes the DNA Polymerase III Gamma-Tau Subunits. The gamma subunit is a component of the gamma complex subassembly that assembles the ring-shaped beta subunit onto ssDNA to form the beta sliding clamps. The tau subunit has multiple functions:enabling processive lagging strand synthesis of DNA replication, blocking beta binding when synthesis is complete, binding to DNA Helicase dnaB to speed up DNA synthesis, protects the beta sliding clamps from removal to produce longer DNA strands, and may stabilize primer-template interaction in DNA replication.

dnaX (EG10245) encodes the DNA Polymerase III Gamma-Tau Subunits. The gamma subunit is a component of the gamma complex subassembly that assembles the ring-shaped beta subunit onto ssDNA to form the beta sliding clamps. The tau subunit has multiple functions:enabling processive lagging strand synthesis of DNA replication, blocking beta binding when synthesis is complete, binding to DNA Helicase dnaB to speed up DNA synthesis, protects the beta sliding clamps from removal to produce longer DNA strands, and may stabilize primer-template interaction in DNA replication.

holA This gene encodes for DNA Polymerase III delta subunit, which is part of the DNA Polymerase III preinitiation complex. Within the preinitation complex, the delta subunit helps remove and attach beta sliding clamps onto ssDNA for processive DNA polymerization to occur.

holA This gene encodes for DNA Polymerase III delta subunit, which is part of the DNA Polymerase III preinitiation complex. Within the preinitation complex, the delta subunit helps remove and attach beta sliding clamps onto ssDNA for processive DNA polymerization to occur.

dnaX This gene encodes for DNA Polymerase III gamma and tau subunits, which play a variety of roles within the DNA Polymerase III holoenzyme. The tau subunit is responsible for binding to the core enzyme to DNA, is required for processive lagging strand synthesis, and is necessary for releasing the polymerase from the beta clamp. Tau also binds the replicative DNA helicase DNA, which allows DNA synthesis to proceed at its normal rate of one thousand nucleotides per second. The gamma subunit, on the other hand, helps assemble ring-shaped beta subunits around ssDNA.

dnaX This gene encodes for DNA Polymerase III gamma and tau subunits, which play a variety of roles within the DNA Polymerase III holoenzyme. The tau subunit is responsible for binding to the core enzyme to DNA, is required for processive lagging strand synthesis, and is necessary for releasing the polymerase from the beta clamp. Tau also binds the replicative DNA helicase DNA, which allows DNA synthesis to proceed at its normal rate of one thousand nucleotides per second. The gamma subunit, on the other hand, helps assemble ring-shaped beta subunits around ssDNA.

pcrA pcrA encodes a DNA helicase protein that is responsible for separating the opposing strands of DNA during cell division.

helD helD encodes an ATP-driven DNA helicase IV protein that is responsible for separating the opposing strands of DNA for cell division.

dnaG dnaG encodes a DNA primase protein that catalyzes the synthesis of short RNA molecules to use as primers during DNA replication.