Glucose transport & catabolism

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  • MMSYN1_0213 , EG10258 The eno gene codes for enolase, an enzyme that catalyzes the interconversion of 2-phosphoglycerate and phosphoenolpyruvate. This occurs during the processes of gluconeogenesis and glycolysis.
  • MMSYN1_0233 ptsP encodes the phosphoenolpyruvate-protein phosphotransferase enzyme. This enzyme catalyzes the reaction between phosphoenolpyruvate and protein L-histidine to create pyruvate.
  • MMSYN1_0234 crr codes for the glucose-specific phosphotransferase enzyme IIA component in the PTS system. This enzyme catalyzes the reaction transporting glucose into the cell.
  • EG12188 ptsP encodes the phosphoenolpyruvate-protein phosphotransferase enzyme. This enzyme catalyzes the reaction between phosphoenolpyruvate and protein L-histidine to create pyruvate.
  • EG10165 crr codes for the glucose-specific phosphotransferase enzyme IIA component in the PTS system. This enzyme catalyzes the reaction transporting glucose into the cell.
  • MMSYN1_0821: This gene encodes hprK. This enzyme phosphorylates HPr, an essential phosphoryl-group carrier in the PTS system.
  • EG10789: This gene encodes ptsI, an enzyme that is part of the PTS system. It catalyzes the phosphorylation of HPr, which is a phosphoryl-group carrier.
  • MMSYN1_0694 The gene ptsH codes for HPr, a histidine and phosphocarrier protein, that can switch between two metabolic strategies available to the cell when utilizing sugars, thereby directing carbohydrate uptake and consumption.
  • EG10788 This gene is the E. coli homolog of the one listed directly above: the gene ptsH codes for HPr, a histidine and phosphocarrier protein, that can switch between two metabolic strategies available to the cell when utilizing sugars, thereby directing carbohydrate uptake and consumption.
  • MMSYN1_0221: The gene pykF codes for pyruvate kinase I, which catalyzes the glycolysis pathway, eventually producing ATP. This particular enzyme operates with fructose as a substrate, as opposed to its sister gene pykA, which codes for an enzyme that operates on glucose.
  • EG10804 This gene is the E. coli homolog of the one listed directly above: it codes for pyruvate kinase I, which catalyzes glycolysis with fructose as a substrate and eventually produces ATP (energy for the cell).
  • MMSYN1_0220, EG10699 The gene produces the ATP-dependent 6-phosphofructokinase enzyme. 6-phosphofructokinase catalyzes the first step of glycolysis, that is, the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP:
  • MMSYN1_0607: The gene encodes for the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate.
  • EG10367: The gene is primarily involved in the oxidative phosphorylation of glyceraldehyde 3-phosphate in glycolysis.
  • MMSYN1_0779 , EG10787: Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule within the cellular membrane to facilitate in the PTS process of phosphorylation carbohydrates into the cellular membrane.
  • MMSYN1_0729, EG12296: This gene is involved in step 3 of a subpathway of glycolysis that synthesizes pyruvate from D-glyceraldehyde 3-phosphate. Specifically, it catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.