Metabolic process

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  • yigL yigL, from E. coli, encodes for pyridoxal phosphate phosphatase, which catalyzes the dephosphorylation of pyridoxal-phosphate
  • glf: encodes for UDP-galactopyranose mutase, an enzyme that is critical in the biosynthesis of galactofuranose in JCVISyn3.0.
  • glf: encodes for UDP-galactopyranose mutase, an enzyme that is critical in the biosynthesis of galactofuranose in E. Coli.
  • nanE: nanE encodes for putative N-acetylmannosamine-6-phosphate 2-epimerase, whose role is to convert N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. It is essential in N-acetylneuraminate degradation, which is itself part of Amino-sugar metabolism. (JCVISyn3.0: MMSYN1 0494, E. Coli: EGG7677)
  • GFP: encodes green fluorescent protein, which transduces the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer.
  • pta: Involved in acetate metabolism. Catalyzes the reversible interconversion of acetyl-CoA and acetyl phosphate.
  • pta: Involved in acetate metabolism. Catalyzes the reversible interconversion of acetyl-CoA and acetyl phosphate.
  • MMSYN1_0227 : The pyruvate dehydrogenase complex in Mycoplasma Mycoides is one of the most complex and complicated enzyme systems known. The self-assembling complex links glycolysis to the TCA cycle (also known as the Krebs cycle or the citric acid cycle).
  • EG10025 : The pyruvate dehydrogenase complex in E. Coli is one of the most complex and complicated enzyme systems known. The self-assembling complex links glycolysis to the TCA cycle (also known as the Krebs cycle or the citric acid cycle).
  • MMSYN1_0262 : Ribulose-5-phosphate 3-epimerase (Rpe) of Mycoplasma Mycoides is an enzyme of the non-oxidative branch of the pentose phosphate pathway. This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle.
  • EG11960 : Ribulose-5-phosphate 3-epimerase (Rpe) of E. Coli is an enzyme of the non-oxidative branch of the pentose phosphate pathway. This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle.
  • RMCFA 4790 : This gene codes for proteins that are found involved with steroid synthesis in flies.
  • galE: This gene works with galactose metabolism
  • MMSYN1_0606: This gene encodes for pgk, a kinase that is part of the pyruvate synthesis pathway.
  • EG10703: This gene econdes for pgk, a kinase that is part of the pyruvate synthesis pathway in E. coli.
  • EC paomart FGFR4 This gene helps with skin regenaration, absorption of vitamin D and many other tissue related things. It's one of the 11 genes in the Mexican Axolotl that exhibits high expression levels when it's undergoing the process of regenerating limbs.
  • EC paomart HBB This gene is found in humans and creates a subunit of hemoglobin, which is essential for the transfer of oxygen from the lungs to tissues across the body.
  • aroA This gene is involved in a late step of chorismate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
  • rpsL This enzyme functions in the general metabolic processes, particularly in transferring an acetyl group from acetyl-CoA to a variety of substrates.
  • MMSYN1_0033 It is a multicopy suppressor of a cold-sensitive secG mutant and also able to suppress fabA6, a temperature-sensitive unsaturated fatty acid auxotroph.
  • gnsA It is a multicopy suppressor of a cold-sensitive secG mutant and also able to suppress fabA6, a temperature-sensitive unsaturated fatty acid auxotroph.
  • galE The gene converts sugars from glucose to galactose
  • edd gene encodes for phosphogluconate dehydratase, which converts D-gluconate 6-phosphate into 2-dehydro-3-deoxy-D-gluconate 6-phosphate and H2O. 2-dehydro-3-deoxy-D-gluconate can eventually be converted into pyruvate by other enzymes for metabolic purposes
  • ppa This gene encodes the protein Inorganic pyrophosphatase (Ppase) which catalyzes the hydrolysis of inorganic pyrophosphate to two orthophosphates. This protein is a key component in DNA, RNA, and protein synthesis.
  • ppa (E. coli) This gene encodes the protein Inorganic pyrophosphatase (Ppase) which catalyzes the hydrolysis of inorganic pyrophosphate to two orthophosphates. This protein is a key component in DNA, RNA, and protein synthesis.
  • nagB This gene encodes the protein that catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate
  • nagB (E. Coli) This gene encodes the protein that catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate and can serve as the sole source of carbon for E. coli
  • deoC This gene encodes an aldehyde lyase enzyme involved in pentose phospate pathway, an important metabolic pathway similar to glycolysis.
  • deoC (E.coli) This gene is produces deoxyribose phosphate adolase, which catalyzes the second step of the pentose phosphate pathway in E.coli
  • ldpa ldpA encodes for Dihydrolipoamide dehydrogenase (DLD), a mitochondrial enzyme that oxidizes dihydrolipoamide to lipoamide. DLD contributes to 5 major enzymatic subunits involved in energy metabolism, such as glycolysis.
  • ldpA (E.coli) ldpA produces dihydrolipoyl dehydrogenase, an oxidoreductase enzyme that converts dihydrolipoamide to lipoamide. This enzyme localizes to the inner membrane and cytosol in E.coli, and plays a vital role in energy metabolism, contributing to 5 metabolic enzyme complexes.
  • MMSYN1_0302 This JCVI gene of unknown function likely contributes to metabolism given its broad characteristic as a flavin reductase, that makes contact with FAD and NADPH cofactors.
  • fre In E.coli, the fre gene encodes for NADPH-flavin reductase (Fre), serving as an electron transfer mediator. Therefore Fre likely contributes to several metabolic pathways
  • tkt This gene produces an enzyme (transketolase) that catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor. Transketolase is a vital enzyme as it functions in the Calvin cycle of photosynthesis.
  • tkt (E. coli) This gene produces an enzyme named transketolase that catalyzes the reversible transfer of a ketol group between donor and acceptor substrates. It is a reversible link between glycolysis and the pentose phosphate pathway.
  • rplB Acts as a proton acceptor and proton donor. Catalyzes the interconversion of ribulose-5-P and ribose-5-P, as part of the Calvin cycle (reductive pentose phosphate pathway) in the oxidative pentose phosphate pathway.
  • rplA (E. coli) Involved in the first step of the non-oxidative branch of the pentose phosphate pathway. It catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  • ackA Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
  • ackA (E. coli) Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.