Nucleotide salvage

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  • G6856: This enzyme has a putative function of degrading cellular membrane proteins.
  • NrdE_NrdA: This gene codes for the alpha subunit of a reductase enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides.
  • tmk: This enzyme plays a role in the dttp/dtmp pathway that is an important step in the formation of DNA from RNA.
  • dctD: dctD encodes an enzyme to catalyze the deamination of dCMP to dUMP, preserving the deoxynucleotide supply.
  • cdd: cdd encodes an enzyme to catalyze the deamination of cytidine to uridine, and deoxycytidine to deoxyuridine, preserving the nucleotide and deoxynucleotide supply.
  • gmk: gmk encodes an enzyme to catalyze the transfer of a phosphate group from ATP to GMP, allowing for GMP recycling.
  • gmk: gmk encodes an enzyme to catalyze the transfer of a phosphate group from ATP to GMP, allowing for GMP recycling.
  • dUTP diphosphatase MMSYN1 0447: Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
  • nudI EG13275: Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
  • nrdF: This protein salvages nucleotides and catalyzes redox reactions.
  • UMP kinase: This protein acts as a catalyst for the reaction that turns ATP and UMP into ADP and UDP.
  • apt: Adenine phosphoribosyltransferase (apt) catalyzes a salvage reaction resulting in the formation of AMP, thus maintaining nucleotide pool balance.
  • prs: Ribose-phosphate diphosphokinase (Prs) is involved in nucleotide synthesis.
  • hpt: Encodes the protein transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate.
  • PyrG: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  • pyrG: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  • HGPRT: Encodes the protein transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate.