RRNA modification

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  • rluD (MMSYN1_0517) encodes large ribosomal subunit pseudouridine synthase D, which catalyzes the synthesis of pseudouridine from uridine and is important for ribosomal assembly.
  • rluD (EG12098) encodes large ribosomal subunit pseudouridine synthase D, which catalyzes the synthesis of pseudouridine from uridine and is important for ribosomal assembly.
  • rlmC catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
  • rsuA creates pseudouridine from uracil-516 in 16S ribosomal RNA.
  • rlub creates pseudoruridine from uracil in 23s ribosomal RNA.
  • rsmG Responsible for methylation of the N7 position of guanine in position 527 in the 530 loop of bacterial 16S rRNA.
  • gidB Methylates the N7 position of guanine in position 527 in the w530 loop of 16S rRNA
  • rsmH JCVI Methylates the N4 position of cytidine-1402 in 16S rRNA (JCVI).
  • rsmH E. Coli Methylates the N4 position of cytidine-1402 in 16S rRNA (E. Coli).
  • pheS Alpha subunit of the phenylalanine-tRNA ligase, an enzyme which catalyzes the formation of an ester linkage between phenylalanine and its appropriate tRNA molecule; the alpha subunit binds phenylalanine and ATP.
  • pheS Alpha subunit of the phenylalanine-tRNA ligase, an enzyme which catalyzes the formation of an ester linkage between phenylalanine and its appropriate tRNA molecule; the alpha subunit binds phenylalanine and ATP.
  • rluD (EG12098 jsdeng) encodes the large ribosomal subunit pseudouridine synthase D, which catalyzes the synthesis of 23S rRNA pseudouridine from 23S rRNA uridine, thus helping with ribosome assembly.
  • MMSYN1 0263 autumng assists in the late maturation steps of the functional core of the 30S ribosomal subunit.
  • YhaM is involved in L-cysteine detoxification.
  • YhaM is involved in L-cysteine detoxification.
  • rlmH catalyzes the addition of a methyl group in the N3 position of pseudouridine residue. Its the only currently known methylated pseudouridine residue in bacterial RNAs.
  • rlmh(Ecoli) does the same as the rlmH above but in an Ecoli cell instead of Mycoplasma.
  • trmH (spoU) is a methyltransferase and type II enzyme that can only modify a subset of certain tRNAs.
  • rnc encodes ribonuclease III in Mycoplasma mycoides, which participates in the double-stranded rRNA cleavage; in particular it cleaves 16S and 23S rRNA prior to incorporation in the ribosome. (also listed under functional category RNA metabolism, which is not visible under the sidebar)
  • rnc encodes ribonuclease III, which cleaves both some types of met-tRNAs and 16S and 23S rRNAs in E. coli in order to produce intermediates to mature rRNAs and metY tRNAs. (also listed under functional category RNA metabolism, which is not visible under the sidebar)
  • ksgA (JCVI) encodes a methyltransferase which methylates two adjacent adenines in 16S rRNA.
  • rsmA (E Coli) encodes a methyltransferase with methylates two adjacent adenins in 16S rRNA in E Coli and is involved 30S subunit regulation.
  • rsmD (JCVI) encodes methyltransferase which methylates the guanine at position 966 of the 16S rRNA
  • rsmD (E Coli) encodes a methyltransferase which methylates the G at position 966 of the 16S rRNA and helps stabilize the binding of the initiator tRNA to the 30S subunit.
  • methyltransferase (unspecified) This gene codes for a protein called Methyltransferase that has a large range of capabilities, including transcription, gene stability, and parental imprinting. No specific methyltransferase (DNA, rRNA, etc.) was found.
  • rlmN The gene rlmN codes for a methyltransferase that causes the methylation of 23S rRNA at the C2 position of the A2503 nucleotide. Additionally, it is responsible for the methylation of certain tRNAs at the C2 position of A37.