Ribosome biogenesis

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  • MMSYN1_0403 Era encodes for the essential GTPase Era that plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis by modifying ribosomal RNA precursors to generate functional 16S rRNA.
  • EG10270 Era in E. coli encodes for the essential GTPase Era that plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis by modifying ribosomal RNA precursors to generate functional 16S rRNA.
  • MMSYN1_0301 RimP encodes for the Ribosome Maturation Factor RimP, which is an important auxiliary protein for maturation of the 30S ribosomal subunit that causes several late-binding proteins to bind rRNA faster, including S9 and S19.
  • EG11179 RimP in E. coli encodes for the Ribosome Maturation Factor RimP, which is an important auxiliary protein for maturation of the 30S ribosomal subunit that causes several late-binding proteins to bind rRNA faster, including S9 and S19.
  • rpIV encodes Ribosomal Protein L22. L22 is a constituent protein of the 50S subunit of the ribosome; more specifically, it lines the ribosome's polypetide exit tunnel.
  • ychF encodes ychF, an ATPase that binds to both ribosomal subunits. Though its exact purpose is yet unknown, it is thought to provide energy for the ribosome via the dephosphorylation of ATP into ADP.
  • MMSYN1_0363 RimM in JCVI encodes an accessory protein that assists in the biogenesis of the head region of the 30S ribosomal subunit (smaller subunit). It plays a significant role in efficient processing of 16S rRNA.
  • EG11153 RimM in E. coli encodes an accessory protein that assists in the biogenesis of the head region of the 30S ribosomal subunit (smaller subunit). It plays a significant role in efficient processing of 16S rRNA.
  • deaD JCVI Catalyzes ATP hydrolysis in order to unwind ATP, which participates in a variety of other processes, including including ribosome biogenesis, mRNA degradation and translation initiation (JCVI).
  • deaD E. Coli Catalyzes ATP hydrolysis in order to unwind ATP, which participates in a variety of other processes, including including ribosome biogenesis, mRNA degradation and translation initiation (E. Coli).
  • rbfA JCVI is one of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.
  • EG13655 is an endoribonuclease that helps with late-stage ribosome quality control and maturation of the 3' strand of rRNA.
  • EG10859 is a subunit of ribonuclease E, which is required for the maturation of 5S and 16S rRNAs and the majority of tRNAs.
  • MMSYN1 0003 is part of ribonuclease M5, which is catalyses 5S rRNA maturation.
  • MMSYN1 0402 is an endoribonuclease that helps with late-stage 70S ribosome quality control and maturation of the 3' strand of 16S rRNA.
  • rnpA is the protein component of RNase P; it aids the removal of the 5' leader sequence of pre- tRNA to produces the mature form of the t-RNA's 5' terminus.
  • rnpA is the protein component of RNase P - it catalyzes the removal of the 5' leader sequence of pre-tRNAs to leave a mature 5'-terminus.
  • MMSYN1 0348 autumng produces GTPase that plays an essential role in the late steps of ribosome biogenesis via GTP binding.
  • EG0348 assembles GTPases that are essential for cell growth and genetic perturbation of their genes confers generally similar phenotype.
  • MMSYN1_0215: a nuclease involved in processing of the 5'-end of pre-16S rRNA
  • ylqF: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. Additionally, this entry contains Escherichia coli (strain K12) RsgA, which plays a role in the late maturation steps of the functional core of the 30S ribosomal subunit.
  • cgtA: A universal, mostly one-gene-per-genome GTP-binding protein that associates with ribosomal subunits and appears to play a role in ribosomal RNA maturation.