From BioE80 Boot
Revision as of 16:04, 1 May 2017 by Acjs (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search

The JCVI-Syn3.0 synthetic cells reported by C.A. Hutchison III et al. in 2016 [1] are documented at the JCVI website. The cell line is commercially available from SGI-DNA. Note that these cells can be purchased for research use; the cost is $1,875.

The authors of the minimal genome paper recently released a perspectives paper, outlining their view on synthetic cells, in Minimal Cells—Real and Imagined.[2] It provides a good overview of the history of the field, and the potential that lies in identifying genes of unknown function in JCVI-Syn3.0.

The database of genes analysed in Design and synthesis of a miminal bacterial genome, and of genes used in the final JCVI-Syn3.0 design, is available at A copy of the database is also available at File:Aad6253-Hutchison-SM-database-S1.xlsx.


  1. C.A. Hutchison III et al. Design and synthesis of a minimal bacterial genome. Science. Vol. 351, March 25, 2016, p.1414. doi: 10.1126/science.aad6253
  2. Glass, John I., et al. "Minimal Cells—Real and Imagined." Cold Spring Harbor Perspectives in Biology (2017): a023861.