Transcription

From BioE80 Boot
Jump to: navigation, search
  • RpoA JCVI: RpoA encodes the alpha subunit of DNA-dependent RNA polymerase (RNAP) that catalyzes the transcription of DNA into RNA. This subunit plays a role in transcriptional initiation and termination, and is important role in RNAP assembly.
  • RpoA E. Coli: RpoA encodes the alpha subunit of DNA-dependent RNA polymerase (RNAP) that catalyzes the transcription of DNA into RNA. This subunit plays a role in transcriptional initiation and termination, and is important role in RNAP assembly.
  • rpoB JCVI, rpoB E.coli: rpoB encodes the beta subunit of DNA-directed RNA polymerase, which transcribes DNA into RNA. The rpoB subunit interacts with DNA in the enzyme active site, contributes to RNA polymerase assembly, and plays a role in initiation of transcription.
  • rpoC JCVI, rpoC E.coli: rpoC encodes the beta subunit of DNA-directed RNA polymerase, which transcribes DNA into RNA. The rpoC subunit interacts with DNA in the enzyme active site, plays a role in initiation of transcription, and coordinates magnesium and zinc ions.
  • nusG JCVI: nusG is a termination/antitermination protein that is involved in Rho-dependent termination. nusG also increases the rate of transcriptional elongation when Rho is not present.
  • nusG E. Coli: nusG is a termination/antitermination protein that is involved in Rho-dependent termination. nusG also increases the rate of transcriptional elongation when Rho is not present.
  • rspK rspK plays a key role in the structure of rRNA ribosomal production, specifically the alpha operon. It is one of the most highly conserved genes on record, from an evolutionary perspective.
  • MMSYN1 0646 This gene creates a protein that assists in the binding of rRNA polymerase, which allows for more reliable protein synthesis.
  • greA JCVI is a transcription factor that possesses transcription elongation activity to allow RNA polymerase to bypass arresting sites in the DNA.
  • nusA JCVI is a transcription factor with termination and antitermination activity.
  • greA E. coli greA in E. coli is a transcription factor that frees RNA polymerase from arresting sites in DNA. It is considered an elongation factor.
  • nusA E. coli is a transcription factor with termination and antitermination activity, as well as activity in ribosomal RNA synthesis and DNA repair.
  • rpoE JCVI Modulates the frequency, rate and extent of cellular DNA-templated transcription. Furthermore, it specializes in response to heat shock and other membrane stresses.
  • rpoE E. coli Modulates the frequency, rate and extent of cellular DNA-templated transcription. Furthermore, it specializes in response to heat shock and other membrane stresses.
  • rpoD JCVI Has a strong interaction with the RNA polymerase and is key to the growth of the organism.
  • rpoD E. coli Has a strong interaction with the RNA polymerase and is key to the growth of the organism.
  • nusB JCVI Involved in the transcription termination process. One of the proteins essential for the formation of the RNA polymerase antitermination complex in the presence of lambda phage N protein. However, it is involved in the transcription termination process at certain sites during normal bacterial growth.
  • rhsD: Encodes hydrophilic proteins with repetitive sequence elements and divergent C-termini.
  • Alsr: negatively controls the expression of genes involved in transport and catabolism of D-allose and low-affinity transport of D-ribose
  • Fis (Extra Credit) Fis encodes for a small DNA-binding transcription factor, FIS. FIS is involved in the up-regulation of hundreds of genes, as well in the structure and maintenance of DNA.
  • FNR (Extra Credit) FNR encodes for fumarate and nitrate reductase, a oxygen-controlled transcription factor involved in the activation of hundreds of genes.